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Priority One's Biofilm Phase-2 Advanced supplement is specifically formulated as an advanced biofilm disruptor.*


Biofilms form and evolve from early (Phase-1 weaker) to later (Phase-2 stronger) forms. These biofilm buster supplements were formulated using the most recent scientific data on biofilm disruption in advanced (Phase-2) cases. 


Contains: Alpha Lipoic Acid, Black Cumin, Bismuth Subnitrate,


Recommended dosing is 2-4 capsules on an empty stomach with a full glass of water, four days weekly or as clinically indicated.

Biofilm Phase-2 Advanced

Excluding Sales Tax |
  • Biofilms are complex communities of microorganisms, including bacteria and fungi, that adhere to surfaces forming a protective matrix that can be difficult to disrupt. In the context of small intestinal bacterial overgrowth (SIBO), biofilms can contribute to the persistence and recurrence of bacterial overgrowth and make treatment more challenging. Here's why biofilm busters are important in managing SIBO:

    • Increased Resistance: Biofilms provide a protective environment for bacteria, making them more resistant to treatments. Bacteria within biofilms exhibit reduced susceptibility to treatment, decreased metabolic activity, and the presence of enzymes that degrade antimicrobial agents.
    • Chronic Overgrowth and Relapse: Biofilms can serve as reservoirs for microbes, allowing them to persist in the gastrointestinal (GI) tract despite treatments. Even if initial antibiotic therapy successfully reduces bacterial overgrowth, residual bacteria within biofilms may lead to chronic overgrowth and recurrent SIBO. Biofilm-associated overgrowths are often more difficult to treat and more prone to relapse than free-floating bacterial infections.
    • Impaired Nutrient Absorption: Biofilms can impair nutrient absorption and disrupt normal GI function. The presence of biofilms in the small intestine may interfere with the absorption of nutrients, vitamins, and minerals, leading to malabsorption and nutritional deficiencies. This can contribute to symptoms commonly associated with SIBO such as bloating, abdominal pain, diarrhea, and weight loss.
    • Inflammatory Response: Biofilms can trigger an inflammatory response in the GI tract, leading to tissue damage and inflammation. The presence of biofilms may exacerbate inflammation in individuals with SIBO, contributing to the development of GI symptoms and complications such as leaky gut syndrome, intestinal permeability, and autoimmune reactions.
    • Treatment Resistance: Biofilms can protect bacteria from the host immune system and antimicrobial therapy, making them more resistant. Standard treatments may be less effective against biofilm-encased microbes leading to treatment failure and persistent symptoms. Biofilm busters, which disrupt biofilm formation and enhance the susceptibility of microbes to antimicrobial agents, may improve the efficacy of SIBO treatment.
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