Estrogen metabolism plays a critical role in hormonal balance and overall health. When this finely tuned process falters, it can lead to estrogen dominance—contributing to symptoms like weight gain, mood swings, and reproductive issues. This article explores how the liver, gut, genetics, and lifestyle factors affect estrogen detoxification and offers natural strategies to support optimal hormone health.

SIBO doesn’t just cause digestive issues—it can also disrupt hormone balance by interfering with estrogen metabolism. It impacts the estrobolome, increases estrogen recirculation, impairs liver detox, and raises inflammatory metabolites. SIBO-related inflammation also raises cortisol, which suppresses sex hormones. Addressing SIBO can support hormone health, restore balance, and relieve symptoms like PMS, low libido, and irregular cycles.