Many people don’t realize the gallbladder plays a key role in hormone balance and gut health. Bile, produced by the liver and stored in the gallbladder, helps detoxify estrogen and keeps bacteria in check in the small intestine. When bile flow is sluggish, it can lead to bloating, estrogen dominance, and conditions like SIBO. Supporting bile production with herbs, supplements, and liver-friendly foods is essential for relieving digestive issues and restoring hormonal balance.

SIBO doesn’t just cause digestive issues—it can also disrupt hormone balance by interfering with estrogen metabolism. It impacts the estrobolome, increases estrogen recirculation, impairs liver detox, and raises inflammatory metabolites. SIBO-related inflammation also raises cortisol, which suppresses sex hormones. Addressing SIBO can support hormone health, restore balance, and relieve symptoms like PMS, low libido, and irregular cycles.

Nutrient malabsorption caused by SIBO leads to a wide variety of clinical complaints on top of the GI distress caused by SIBO itself.

Understanding the difference between SIBO reactions and immune responses to food is key to treating the root cause of GI distress.